Anant Madabhushi is the F. Alex Nason professor II of biomedical engineering at Case Western Reserve University in Cleveland and director of the university’s Center for Computational Imaging and Personalized Diagnostics (CCIPD). He is also a Research Scientist at the Louis Stokes Cleveland Veterans Administration (VA) Medical Center and has affiliate appointments both at University Hospitals and Cleveland Clinic.
Dr. Madabhushi’s team has developed pioneering computer aided diagnosis, pattern recognition, image analysis tools for diagnosis and prognosis of different types of cancers (prostate, breast, medulloblastoma, oropharyngeal) based on quantitative and computerized histomorphometric image analysis of digitized histologic biopsy tissue specimens as well as from radiographic scans such as MRI and CT images. This novel approach involves quantitatively mining sub-visual patterns from image data for via sophisticated image segmentation, feature extraction, machine learning and pattern recognition methods and then predicting disease presence but also the risk of disease recurrence and patient outcome and therapeutic response.
Madabhushi has nearly 100 patents either issued or pending in the areas of medical image analysis, computer-aided diagnosis, and computer vision and currently holds >40 issued patents in medical imaging analysis, computer vision and computer-aided diagnosis. He was responsible for 10 percent of all patents awarded at Case Western Reserve University in 2017 and 2018.
The author of over 350 peer-reviewed journal articles and conference papers, Madabhushi is a sought after lecturer who has delivered over 280 talks around the world. His efforts as a professor and researcher have gained international attention in the field of biomedical engineering, garnering him several awards. Most notably, Madabhushi is a Wallace H. Coulter Fellow, a fellow of the American Institute of Medical and Biomedical Engineering (AIMBE), and a Fellow of the Institute of Electrical and Electronics Engineers (IEEE). In 2015, he made Crain’s Business Cleveland magazine’s “Forty under 40” list. Dr. Madabhushi’s work on developing “smart computers for identifying lung cancer patients who will benefit from chemotherapy” was ranked as one of the top 10 medical breakthroughs of 2018 by Prevention Magazine. In 2019 Nature Magazine called him out as one of 5 scientists pursuing truly offbeat and innovative approaches in cancer research. In September 2019, Madabhushi was named to The Pathologist's Power List 2019, a list of 100 most inspiring professionals in pathology and laboratory medicine.
Madabhushi has secured more than $50 million in grant funding and co-founded two companies, Vascuvis Inc. (now Elucid Bioimaging) and IbRiS Inc., which was acquired by Inspirata in 2015. He has been involved in several sponsored research and industry partnerships medical imaging and pharmaceutical companies. In addition, more than 15 technologies developed by Madabhushi’s team have been licensed.